Two New Orleans paramedics' lives are ripped apart after encountering a series of horrific deaths linked to a designer drug with bizarre, otherworldly effects.

Young immigrant Rahui and his pregnant sister are attacked and separated by a demonic spirit as they embark on a dangerous trek across the U.S. border. Injured but determined to survive, Rahui must rescue his sister before the demon takes the one thing she was denied in life–a baby.